New Nervogenic Acid Derivatives from Liparis nervosa

作者:Huang, Shuai; Zhou, Xian-li*; Wang, Cui-juan; Wang, Hong-yan; Wang, You-song; Shan, Lian-hai; Weng, Jie
来源:Planta Medica, 2013, 79(3-4): 281-287.
DOI:10.1055/s-0032-1328109

摘要

Ten new nervogenic acid derivatives (1-4, 6-11) and one known compound (5) have been isolated from Liparis nervosa. Their structures were determined using extensive spectroscopic analysis, including 1D and 2D NMR experiments. Compounds 3, 4, 9, 10, and 11 were evaluated for their cytotoxicity against A549, H460, Hela, MCF-7, Ca-co2, and HepG2 human cancer cell lines.