科研之友
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摘要
MM To assess the benefits and limits of surgery for primary hepatic lymphoma (PHL), and probability of survival after postoperative chemotherapy
METHODS A retrospective analysis was undertaken to determine the results of surgical treatment of PHL over the past 8 years Only nine patients underwent such treatment The detailed data of diagnosis, treat merit, and prognosis were carefully studied
RESULTS All patients were mistaken as having a fetoprotein negative hepatic cancer before pathological diagnosis The mean delay time between initial symptoms and final diagnosis was 26 8 d (range 14 47 d) Hepatitis B virus infection was noted in 33 3% of these patients Most of the lesions were found to be restricted to a solitary hepatic mass The surgical procedure per formed was left hepatectomy in five cases, including left lateral segmentectomy in three Right hepatectomy was performed in three cases and combined procedures in one One patient died on the eighth day after surgery, secondary to hepatic insufficiency The cumulative 6 mo, 1 year, and 2 year survival rates after hepatic surgery were, respectively, 85 7%, 71 4%, and 47 6% One patient survived for > 5 years after surgery without any signs of recurrence until latest follow up, who received routine postoperative chemotherapy every month for 2 years and then regular follow up By univariate analysis, postoperative chemotherapy was a significant prognostic factor that influenced survival (P = 0 006)
CONCLUSION PHL is a rare entity that is often misdiagnosed, and has a potential association with chr
- 出版日期2010-12-21
- 单位中国人民解放军第二军医大学
