Genetic Inheritance Effects on Endurance and Muscle Strength An Update

作者:Costa Aldo M; Breitenfeld Luiza; Silva Antonio J; Pereira Ana; Izquierdo Mike*; Marques Mario C
来源:Sports Medicine, 2012, 42(6): 449-458.

摘要

Top-level sport seems to play a natural Darwinian stage. The most outstanding athletes appear to emerge as a result of exogenous influences of nature and/or coincidence, namely, the contingency of practicing certain sport for which their talents best fit. This coincidence arises because certain individuals possess anatomical, metabolic, functional and behavioural characteristics that are precisely those required to excel in a given sport. Apart from the effects of training, there is strong evidence of genetic influence upon athletic performance. This article reviews the current state of knowledge regarding heritable genetic effects upon endurance and muscle strength, as reported by several twin and family studies. Due, probably, to the inaccuracy of the measurement procedures and sampling error, heritability estimates differ widely between studies. Even so, the genetic inheritence effects seem incontrovertible in most physical traits: similar to 40-70% for peak oxygen uptake and cardiac mass and structure, and similar to 30-90% for anaerobic power and capacity, ranging according to the metabolic category. Studies in development by several researchers at this present time seem to guarantee that future reviews will include twins and family studies concerning genes associated with the adaptive processes against hormetic agents, such as exercise, heat and oxidative stress.

  • 出版日期2012