Degradable fluorescent single-chain nanoparticles based on metathesis polymers

作者：Offenloch Janin T; Willenbacher Johannes; Tzvetkova Pavleta; Heiler Carolin; Mutlu Hatice; Barner Kowollik Christopher

来源：Chemical communications, 2017, 53(4): 775-778.

DOI：10.1039/c6cc08554g

We introduce the facile synthesis of fluorescent single-chain nano-particles (SCNPs) based on chain-shattering acyclic diene metathesis (ADMET) polymers featuring self-immolative azobenzene motifs. An electrophilic alkoxyetherification is utilized to introduce the photo-reactive moieties required for the subsequent chain collapse via UV-induced nitrile imine-mediated tetrazole-ene cycloaddition (NITEC).

• 出版日期2017-1-14