Using the Man(9)(GlcNAc)(2)-DC-SIGN pairing to probe specificity in photochemical immobilization

作者:Dilly Suzanne J; Clark Andrew J; Mitchell Daniel A*; Marsh Andrew; Taylor Paul C
来源:Molecular Biosystems, 2011, 7(1): 116-118.
DOI:10.1039/c0mb00118j

摘要

We demonstrate the expected preference of an immobilised oligosaccharide Man(9)(GlcNAc)(2) upon a 96-well photochemical array, for its known receptor, the cell-surface lectin Dendritic Cell-Specific ICAM3 Grabbing Nonintegrin (DC-SIGN) when compared to immobilised competing monosaccharides.

  • 出版日期2011