A dual near-infrared pH fluorescent probe and its application in imaging of HepG2 cells

作者:Tang Bo*; Liu Xia; Xu Kehua; Huang Hui; Yang Guiwen; An Liguo
来源:Chemical communications, 2007, (36): 3726-3728.
DOI:10.1039/b707173f

摘要

A dual near-infrared pH fluorescent probe has been designed, synthesized and applied to HepG2 cells, with a pK(a) value of 5.14 under acidic conditions and 11.31 under basic conditions, which is valuable for studying acidic organelles in living cells and pH changes in chemical systems.