A case of tophaceous pseudogout of the temporomandibular joint extending to the base of the skull

作者：Kudoh K^*; Kudoh T; Tsuru K; Miyamoto Y

来源：International Journal of Oral and Maxillofacial Surgery, 2017, 46(3): 355-359.

DOI：10.1016/j.ijom.2016.08.018

• calcium pyrophosphate dihydrate
• Fourier transform infrared spectroscopy
• temporomandibular joint
• tophaceous pseudogout
• X-ray diffraction

A case of tophaceous pseudogout (i.e., calcium pyrophosphate dihydrate (CPPD) crystal deposition disease) in the temporomandibular joint (TMJ), extending to the base of the skull, is reported. A 38-year-old man was referred to the hospital with mild pain in the right chin and tip of the tongue. Panoramic radiography showed a large calcified mass around the right TMJ. Computed tomography imaging revealed a large, granular, calcified mass surrounding the right condylar head and extending to the base of the skull. The mass was clinically and radiographically suspected to be a pseudogout lesion. A biopsy specimen was collected under general anaesthesia to confirm the diagnosis. On histology, the mass was found to contain deposits of numerous rod-shaped and rhomboid crystals, which suggested tophaceous pseudogout. The deposits were identified as CPPD crystal deposition, based on analysis by X-ray diffraction and Fourier transform infrared spectroscopy. These two crystallography methods were useful in confirming the diagnosis of CPPD crystal deposition disease in the TMJ.

• 出版日期2017-3