Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

作者:Thompson George R III*; Blair Janis E; Wang Sharon; Bercovitch Robert; Bolaris Michael; Van den Akker Dane; Lopez Rodrigo; Heidari Arash; Catanzaro Antonino; Cadena Jose; Chin Hong Peter; Spellberg Brad; Johnson Royce
来源:Clinical Infectious Diseases, 2017, 65(2): 338-341.
DOI:10.1093/cid/cix318

摘要

Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P = .0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

  • 出版日期2017-7-15
  • 单位UCLA