科研之友
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摘要
Biomaterials are revolutionising many aspects of preventive and therapeutic healthcare. These are the materials with novel properties that make them especially suitable to have an intimate contact with living tissue, and are produced through processes that often employ or mimic biological phenomena. One of the prime requirements of these materials is biocompatibility, that is, the ability of a material to perform with an appropriate response in a specific application. The biomaterials include new medical devices, prostheses, tissue repair and replacement technologies (tissue engineering), drug delivery systems and diagnostic techniques. In all these cases, the underlying theme is the interaction between biosystems and synthetic or modified natural materials. However, there is growing recognition that physical, chemical and structural properties of biomaterials can regulate biological responses and, consequently, determine the ultimate fate of the end products. This article presents a critical review of this transition with regard to selected physical properties including size, shape, mechanical properties, surface texture and compartmentalisation of biomaterials. An attempt has also been made to optimise the structural parameters of the materials which directly translate into performance of the materials in question.
- 出版日期2010-9
