Determination of Anti-Cathepsin-D Antibodies in Human Blood Sera of Oncological Patients

作者：Machova Iva^*; Zidkova Jarmila; Springer Drahomira; Vetvicka Vaclav; Fusek Martin

来源：Chemicke Listy, 2012, 106(8): 769-772.

I. Machova(a,b), J. Zidkova(b), D. Springer(c), V. Vetvicka(d), and M. Fusek(b) ((a)Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, Prague, (b)Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague, (c)Department of Clinical Biochemistry and Laboratory Medicine, First Faculty of Medicine, Charles University, Prague), (d) Department of Pathology, University of Louisville, Louisville, USA): Determination of Anti-Cathepsin-D Antibodies in Human Blood Sera of Oncological Patients In this study the levels of auto-antibodies formed against the activation peptide of procathepsin D were determined by the ELISA method using a synthetic multi-antigen peptide containing the N-terminal amino acid sequence of the activation peptide of procathepsin D as a coating antigen. Based on the results auto-antibodies cannot be considered suitable cancer markers.

• 出版日期2012