Systemic Inflammatory Syndrome Associated with a Case of Jugular Paraganglioma

作者：Sokabe Ayuko; Mizooka Masafumi^*; Sakemi Rinne; Kobayashi Tomoki; Kishikawa Nobusuke; Yokobayashi Kenichi; Kanno Keishi; Tazuma Susumu

来源：Internal Medicine, 2016, 55(15): 2105-2108.

DOI：10.2169/internalmedicine.55.4655

• jugular paraganglioma
• systemic inflammatory syndrome
• interleukin-6
• paraneoplastic syndrome

Jugular paraganlioma is a benign, slow-growing tumor originating from the paraganglion cells and it is associated with catecholamine secretion. Paragangliomas can secrete Interleukin-6 (IL-6) and present as a systemic inflammatory syndrome; these characteristics have not been previously associated with jugular paragangliomas. A 63-year-old man with a jugular tumor in the skull base was referred to our hospital for an evaluation of pyrexia, back pain, and acute inflammation. His serum IL-6 level was elevated on admission and it decreased after radiotherapy. This is the first known case of a jugular paraganglioma exhibiting systemic inflammatory syndrome.

• 出版日期2016