AtROP6 is involved in reactive oxygen species signaling in response to iron-deficiency stress in Arabidopsis thaliana

作者：Zhai, Longmei; Sun, Chaohua; Feng, Yi; Li, Duyue; Chai, Xiaofen; Wang, Lei; Sun, Qiran; Zhang, Guifen; Li, Yi; Wu, Ting; Zhang, Xinzhong; Xu, Xuefeng; Wang, Yi^*; Han, Zhenhai^*

来源：FEBS LETTERS, 2018, 592(20): 3446-3459.

DOI：10.1002/1873-3468.13257

• AtROP6
• iron deficiency
• reactive oxygen species

Understanding the mechanism of iron (Fe)-deficiency responses is crucial for improving plant Fe bioavailability. Here, we found that the Arabidopsis Rho-like GTPase 6 mutant (rop6) is less sensitive to Fe-deficiency responses and has reduced levels of reactive oxygen species (ROS) compared to wild-type (WT), while AtROP6-overexpressing seedlings exhibit more sensitivity to Fe-deficiency responses and has higher levels of ROS compared to WT. Moreover, treatment with H2O2 improves the sensitivity to Fe-deficiency responses in rop6 mutants. By using the yeast two-hybrid system, we further demonstrate the direct interaction between AtROP6 and Arabidopsis respiratory burst oxidase homolog D (AtRBOHD), which controls the generation of ROS. Overall, we suggest that AtROP6 is involved in AtRBOHD-mediated ROS signaling to modulate Fe-deficiency responses in Arabidopsis thaliana.

• 出版日期2018-10
• 单位中国农业大学