Amberlyst-15 catalysed microwave assisted cross-aldol condensation between ketones and aldehydes under solvent free condition

作者：Pal Rammohan; Mandal Tapas K; Guha Chayan; Mallik Asok K^*

来源：Journal of the Indian Chemical Society, 2011, 88(5): 711-717.

• Cycloalkanones
• benzaldehydes
• cinnamaldehyde
• amberlyst-15
• microwave irradiation
• alpha,alpha '-bis(arylmethylene)cycloalkanones
• alpha,alpha '-bis(cinnamylidene)cycloalkanones
• alpha-cinnamylideneacetophenones
• chalcones

Amberlyst-15 has been applied as an efficient heterogeneous catalyst for the first time for rapid synthesis of alpha,alpha'-bis(arylmethylene)cycloalkanones, alpha,alpha'-bis(cinnamylidene)cycloalkanones, alpha-cinnamylideneacetophenones and chalcones in very good yield by the reaction between various aldehydes and ketones under microwave irradiation. The new process for the cross-aldol condensation reaction works well in absence of any solvent. The yields are high and the process is environmentally benign.

• 出版日期2011-5