A simple parallel gas chromatography column screening system

作者：Schafer Wes; Hamilton Simon E; Pirzada Zainab; Welch Christopher J^*

来源：Chirality, 2012, 24(1): 1-4.

DOI：10.1002/chir.21974

• GC
• screening
• method development
• fast analysis

A simple approach to the automated screening of four different columns on a single gas chromatography (GC) instrument is used for rapid chiral GC method development. Configuration of a conventional GC instrument with a second autosampler and several inexpensive Y-splitters enables simultaneous evaluation of two different columns, allowing a total of four different columns to be evaluated in two automated back to back runs. The resulting system affords a simple and effective approach to chiral GC method development that speeds analysis while eliminating the need for slow and tedious manual interchange of columns. An example of developing a rapid isothermal GC method from the screening results obtained by the instrument is also shown. Chirality, 2011.

• 出版日期2012-1