A RANDOMIZED, MULTICENTER, OPEN-LABEL CLINICAL TRIAL TO ASSESS THE ANAMNESTIC IMMUNE RESPONSE 4 TO 8 YEARS AFTER A PRIMARY HEPATITIS B VACCINATION SERIES

作者:Diez Domingo Javier; Flores Sheryl A; Martin Jason C; Klopfer Stephanie O; Schoedel Florian P; Bhuyan Prakash K*
来源:Pediatric Infectious Disease Journal, 2010, 29(10): 972-974.
DOI:10.1097/INF.0b013e3181f1b3b6

摘要

This open-label, randomized study challenged 4- to 8-year-old children from Spain (N = 1478) with a single dose of hepatitis B vaccine to estimate anamnestic responses. At the time of preimmunization, 15.9% to 51.2% of subjects had antibody values >= 10 mIU/mL. One month postimmunization, 91.6% to 97.3% of subjects had antibody titers >= 10 mIU/mL. There were no serious, vaccine-related, adverse experiences, and no discontinuations as a result of adverse experience.

  • 出版日期2010-10

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