Adult Intestinal Transplantation

作者：Matsumoto Cal S^*; Subramanian Sukanya; Fishbein Thomas M

来源：Gastroenterology Clinics of North America, 2018, 47(2): 341-+.

DOI：10.1016/j.gtc.2018.01.011

• Adult intestinal transplantation
• Intestinal transplant indications
• Intestinal transplant outcome
• Virtual crossmatch

Adult intestinal transplant differs significantly from pediatric intestinal transplant. Although indications have remained largely consistent since 2000, indications for adults have expanded over the last 2 decades to include motility disorders and desmoid tumors. Graft type in adult recipients depends on the distinct anatomic characteristics of the adult recipient. Colonic inclusion, although initially speculated to portend unfavorable outcomes due to complex host-bacterial interactions, has increased over the past 2 decades with superior graft survival and improved patient quality of life. Overall, outcomes have steadily improved. For adult intestinal transplant candidates, intestinal transplantation remains a mainstay therapy for complicated intestinal failure and is a promising option for other life-threatening and debilitating conditions.

• 出版日期2018-6