Ni-Catalyzed Reduction of Inert C-O Bonds: A New Strategy for Using Aryl Ethers as Easily Removable Directing Groups

作者:Alvarez Bercedo Paula; Martin Ruben*
来源:Journal of the American Chemical Society, 2010, 132(49): 17352-17353.
DOI:10.1021/ja106943q

摘要

An efficient Ni-catalyzed protocol for the reductive cleavage of inert C-O bonds has been developed. The method is characterized by its simplicity and wide scope, thereby allowing the use of aryl ethers as easily removable directing groups in organic synthesis.

  • 出版日期2010-12-15