Anti-Ro/SSA antibodies and cardiac rhythm disturbances: Present and future perspectives

作者：Santos Pardo Irene; Villuendas Roger^*; Salvador Corres Inaki; Martinez Morillo Melania; Olive Alejandro; Bayes Genis Antoni

来源：International Journal of Cardiology, 2015, 184: 244-250.

DOI：10.1016/j.ijcard.2014.11.002

• Anti-Ro/SSA
• Pathogenesis
• Cardiac rhythm disturbances

Several case reports, small case series, and original research papers have recently suggested that the action of certain auto-antibodies related to connective tissue diseases may be responsible for significant cardiac rhythm disturbances in adults. The relationship between anti-Ro/SSA antibodies and congenital complete atrioventricular block is well recognized in the fetal heart. Herein we review the emerging evidences of the link to increased levels of anti-Ro/SSA antibodies with rhythm disorders of unknown origin in the adult. Confirmation of this distinct etiology may eventually be the basis for new therapies.

• 出版日期2015-4-1