Directed addition of sulfur-stabilised carbanions to 1,2,3-trisubstituted aziridines

作者：Craig Donald^*; Lu Pengfei; Mathie Tanya; Tholen Niels T H

来源：Tetrahedron, 2010, 66(33): 6376-6382.

DOI：10.1016/j.tet.2010.04.096

• Aziridine
• Cyclisation
• Directed addition
• Regioselective
• Sulfur-stabilised Carbanion

Thioether and sulfone-stabilised carbanions possessing varying functional groups enter into highly regioselective, stereospecific ring-opening reactions with vinyl- and hydroxymethyl-substituted aziridines. Some derivatisation reactions of the adducts are reported.

• 出版日期2010-8-14