A very simple and highly efficient procedure for N-formylation of primary and secondary amines at room temperature under solvent-free conditions

作者：Brahmachari Goutam^*; Laskar Sujay

来源：Tetrahedron Letters, 2010, 51(17): 2319-2322.

DOI：10.1016/j.tetlet.2010.02.119

• N-Formylation
• Amines
• Sodium formate
• Formic acid
• Room temperature
• Solvent-free

N-Formylation of primary and secondary amines has efficiently been carried out at room temperature in excellent yields by using catalytic amount of sodium formate in formic acid under solvent-free conditions. The process is remarkably simple and environmentally benign.

• 出版日期2010-4-28