A peptide hydrogel derived from a fragment of human cardiac troponin C

作者：De Leon Rodriguez Luis M^*; Kamalov Meder; Hemar Yacine; Mitra Alok K; Castelletto Valeria; Hermida Merino Daniel; Hamley Ian W; Brimble Margaret A^*

来源：Chemical Communications, 2016, 52(21): 4056-4059.

DOI：10.1039/c6cc00209a

The human cardiac troponin C peptide fragment H-V(9)EQLTEEQKN EFKAAFDIFVLGA(31)-OH, which covers helix-A in the native protein, self-assembles into b-sheet fibrils in solution. These fibrils further entangle to give a hydrogel. This peptide may therefore serve as a template for development of novel biomaterials.

• 出版日期2016