A New Ferulic Acid Ester and Other Constituents from Dracocephalum pereginum

作者：Dai, Li-Min; Zhao, Chun-Chao; Jin, Hui-Zi; Tang, Jian^*; Shen, Yun-Heng; Li, Hui-Liang; Peng, Cai-Yun; Zhang, Wei-Dong

来源：Archives of Pharmacal Research, 2008, 31(10): 1325-1329.

DOI：10.1007/s12272-001-2113-2

• Dacocephalum peregrinum
• Ferulic acid ester
• 1 '-Methyl-2 '-hydroxyethyl ferulate
• NO production

A new ferulic acid ester, 1'-methyl-2'-hydroxyethyl ferulate (1), together with methylcaffeate (2), 4-hydroxy cinnamic acid (3), ferulic acid (4), caffeic acid (5), diosmetin (6), luteolin (7), 5,3',4'-trihydroxy-3,7-dimethoxyflavone (8), eriodictyol (9), kaempferol (10), quercetin (11), acacetin-7-O-glcopyranoside (12), 4-(beta-glucopyranosyloxy) benzoic acid (13), luteolin-7-0-(6"-feruloyl) glucopyranoside (14), luteolin-7-O-glucopyranoside (15), kaempferide-3-O-rhamnopyranoside (16), quercitrin (17), kaempferol-3-O-glucopyranoside (18), prunasin (19), quercetin-7-O-glucopyranoside (20), quercetin-3-O-glucopyranoside (21), plantaginin (22), linarin (23), luteolin-7-O-rutinoside (24), and chlorogenic acid (25) were isolated from the aerial parts of Dacocephalum peregrinum. The structure of I was elucidated on the basis of spectroscopic and HR-ESI-MS analyses. In addition, compound 1 exhibited mild inhibitory effect on NO production in LPS-stimulated RAW264.7 cells.

• 出版日期2008-10
• 单位湖南中医药大学; 上海交通大学; 中国人民解放军第二军医大学