Noise reduction in multi-slice arterial spin tagging imaging

作者：St Lawrence KS^*; Frank JA; Bandettini PA; Ye FQ

来源：Magnetic Resonance in Medicine, 2005, 53(3): 735-738.

DOI：10.1002/mrm.20396

• arterial spin tagging
• arterial spin labeling
• cerebral blood flow
• blood oxygenation level dependant contrast
• functional magnetic resonance imaging
• physilogical noise

Attenuating the static signal in arterial spin tagging (ASSIST) was initially developed for 3D imaging of cerebral blood flow. To enable the simultaneous collection of cerebral blood flow and BOLD data, a multi-slice version of ASSIST is proposed. As with the 3D version, this sequence uses multiple inversion pulses during the tagging period to suppress the static signal. To maintain background suppression in all slices, the multi-slice sequence applies additional inversion pulses between slice acquisitions. The utility of the sequence was demonstrated by simultaneously acquiring ASSIST and BOLD data during a functional task and by collecting resting-state ASSIST data over a large number of slices. In addition, the temporal stability of the perfusion signal was found to be 60% greater at 3 T compared to 1.5 T, which was attributed to the insensitivity of ASSIST to physiologic noise.

• 出版日期2005-3
• 单位NIH