Msp1: patrolling mitochondria for lost proteins

作者:Hegde Ramanujan S*
来源:The EMBO Journal, 2014, 33(14): 1509-1510.
DOI:10.15252/embj.201488930

摘要

Intracellular protein localization is critical for establishing organelle identity, avoiding inappropriate interactions, and maintaining cellular function. An emerging mechanism for ensuring high-fidelity protein localization is the selective destruction of mislocalized copies. Two new papers find that the mitochondrial outer membrane is kept free of mislocalized proteins by Msp1 (Chen et al, 2014; Okreglak & Walter, 2014).

  • 出版日期2014-7-17

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