A Convenient Hydrogenation Method for the Synthesis of Metallo-mesoporphyrin IX Dimethyl Esters via Self-catalyzed CoCl2-NaBH4 Reagent System

作者：Xu Shichao; Hu Bingcheng^*; Hu Tianjing; Wang Huan; Huang Xiuyou; Lou Xingkun; Liu Zuliang

来源：Chinese Journal of Chemistry, 2012, 30(10): 2461-2465.

DOI：10.1002/cjoc.201200581

• protoporphyrin
• catalytic hydrogenation
• mesoporphyrin
• cobalt chloride
• sodium borohydride

A convenient protocol has been developed for the hydrogenation of metallo-protoporphyrin IX dimethyl esters (MPPDMEs) to their mesoporphyrin analogues using CoCl2-NaBH4 reagent system. Metallo-porphyrin complexes were found to perform as self-catalysts in this procedure. This method provides several advantages such as safe and simple procedure, short reaction time, high yields and low cost.

• 出版日期2012-10
• 单位南京理工大学