Azaindole-1,2,3-triazole conjugate in a tripod for selective sensing of Cl-, H2PO4- and ATP under different conditions

作者：Ghosh Kumaresh^*; Kar Debasis; Joardar Soumen; Samadder Asmita; Khuda Bukhsh Anisur Rahaman

来源：RSC Advances, 2014, 4(23): 11590-11597.

DOI：10.1039/c3ra45018j

A new tripodal sensor 1 has been designed and synthesized. The cavity of the tripod selectively recognizes Cl- and H2PO4- over a series of other anions in CH3CN containing 0.01% DMSO by exhibiting a significant change in emission. Between H2PO4- and Cl- ions, H2PO4- is distinguished by 1 through a ratiometric change in emission. In comparison, the indole-based tripod 2 did not show any binding-selectivity with the same anions. Compound 1, furthermore, selectivity recognizes phosphate based biomolecule ATP over ADP and AMP in semi aqueous solvent (CH3CN containing 0.01% DMSO : H2O, 1 : 1, v/v) at pH 7.3. The tripod 1 is cell permeable and detects ATP by showing quenching of emission.

• 出版日期2014