Detecting cancer by monitoring circulating tumor DNA

作者:Spellman Paul T*; Gray Joe W
来源:Nature Medicine, 2014, 20(5): 474-475.
DOI:10.1038/nm.3564

摘要

DNA that is shed by dead tumor cells into the blood, termed circulating tumor DNA (ctDNA), is a rich resource that could potentially be used for cancer diagnostics and monitoring. A new study describes a sequencing-based method that improves upon the sensitivity and specificity achieved by past techniques for detecting ctDNA and that can be used for monitoring of disease burden in patients with non small-cell lung cancer (pages 548-554).

  • 出版日期2014-5