General synthesis of epi-series catechins and their 3-gallates: reverse polarity strategy

作者:Ohmori Ken; Yano Takahisa; Suzuki Keisuke*
来源:Organic and Biomolecular Chemistry, 2010, 8(12): 2693-2696.
DOI:10.1039/c003464a

摘要

A general synthetic route to the epi-series catechins was developed based on the reverse polarity strategy. Aromatic nucleophilic substitution reaction followed by the sulfinyl metal exchange and cyclization enabled stereo-controlled access to various members of epi-series catechins and their 3-gallates.

  • 出版日期2010-6-21