Hepatitis E Virus in Pork Production Chain in Czech Republic, Italy, and Spain, 2010

作者：Di Bartolo Ilaria; Diez Valcarce Marta; Vasickova Petra; Kralik Petr; Hernandez Marta; Angeloni Giorgia; Ostanello Fabio; Bouwknegt Martijn; Rodriguez Lazaro David; Pavlik Ivo; Ruggeri Franco Maria^*

来源：Emerging Infectious Diseases, 2012, 18(8): 1282-1289.

DOI：10.3201/eid1808.111783

We evaluated the prevalence of hepatitis E virus (HEV) in the pork production chain in Czech Republic, Italy, and Spain during 2010. A total of 337 fecal, liver, and meat samples from animals at slaughterhouses were tested for HEV by real-time quantitative PCR. Overall, HEV was higher in Italy (53%) and Spain (39%) than in Czech Republic (7.5%). HEV was detected most frequently in feces in Italy (41%) and Spain (39%) and in liver (5%) and meat (2.5%) in Czech Republic. Of 313 sausages sampled at processing and point of sale, HEV was detected only in Spain (6%). HEV sequencing confirmed only g3 HEV strains. Indicator virus (porcine adenovirus) was ubiquitous in fecal samples and absent in liver samples and was detected in 1 slaughterhouse meat sample. At point of sale, we found porcine adenovirus in sausages (1%-2%). The possible dissemination of HEV and other fecal viruses through pork production demands containment measures.

• 出版日期2012-8