A New Phenyl Propanoid from the Roots of Nicotiana tabacum and Its Biological Activities

作者：Mou Dingrong; Zhao Wei; Zhang Tao; Liu Wei; Yang Guangyu; Chen Yongkuan; Hu Qiufen^*; Miao Mingming

来源：Asian Journal of Chemistry, 2013, 25(12): 6983-6984.

DOI：10.14233/ajchem.2013.14345

• 3-Hydroxy-1-(4,5-dimethoxyphenyl-2-O-beta-D-glucopyranoside)-propan-1-on e
• Nicotiana tabacum
• Cytotoxicity

A new phenylpropanoid, 3-hydroxy-1-(4,5-dimethoxyphenyl-2-O-beta-D-glucopyranoside)-propan-1-one, was isolated from the roots of Nicotiana tabacum. Its structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. Compound 1 was tested for its cytotoxicity against five human tumor cell lines and it show modest cytotoxic abilities against PC3 and MCF7 cell with IC50 values of 5.6 and 2.8 mu M, respectively.

• 出版日期2013-9
• 单位云南民族大学; 云南省烟草农业科学研究院