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摘要
Objective: To provide a clinical update oil Graves' hyperthyroidism and pregnancy with it focus oil treatment with antithyroid drugs
Methods: We searched the English-language literature for Studies published between 1929 and 2009 related to management of hyperthyroidism in pregnancy In this review. we discuss differential diagnosis of hyperthyroidism management. Importance of early diagnosis. and Importance of achieving proper control to avoid maternal and fetal complications.
Results: Diagnosing, hyperthyroidism during pregnancy can be challenging because many Of the and symptoms are similar to normal physiologic changes that Occur ill pregnancy. Patients with Graves disease require prompt treatment with antithyroid and should undergo frequent monitoring for signs of fetal and maternal hyperthyroidism and hypothyroidism. Rates of maternal and perinatal complications ire directly related to control of hyperthyroidism ill the mother Thyroid receptor antibodies should be assessed ill all women with hyperthyroidism to help predict and reduce the risk of fetal or neonatal hyperthyroidism or hypothyroidism The maternal thyroxine level should be kept Ill the upper third of the reference rank-le or just above normal,11, using the lowest possible antithyroid drug dosage Hyperthyroidism may recur ill the postpartum period as Graves disease or postpartum thyroiditis. this, It is prudent to evaluate thyroid function 6 weeks after delivery approach to care, and patient education regarding approach to care. and patient education regarding potential maternal and fetal complications that call occur with different types of: treatment are Important
Conclusion: Preconception counseling and a multifaceted approach to care by the endocrinologist and the obstetric team are Imperative for it successful pregnancy in women with Graves hyperthyroidism (.Endocr Pract. 2010;16:118-129)
- 出版日期2010-2
