Beyond the Hundred Dollar Genome - Drug Discovery Futures

作者:Selwood David L*
来源:Chemical Biology & Drug Design, 2013, 81(1): 1-4.
DOI:10.1111/cbdd.12088

摘要

The advent of silicon chip based technologies for genome sequencing promises continuing exponential falls in the reagent costs of sequencing. When every patient has a full genome sequence as part of their medical records the science of drug discovery and drug design must adapt and improve to meet this challenge. This series covers computational, and experimental approaches for small molecules and biologics. From the virtual patient a computational model of a complete human being, through in silico screening to RNA editing and antibody directed therapies.

  • 出版日期2013-1