Apelin and PDCD5 levels in patients with chronic heart failure

作者：Yang Guojie^*; Wang Quanhe; Wu Nan; Wei Zihan

来源：Life Science Journal-Acta Zhengzhou University Overseas Edition, 2013, 10(1): 3180-3182.

Objective: To detect the plasma levels of apelin and Programed Cell Death 5(PDCD5) antibody in elderly patients with chronic heart failure. Methods: Forty patients with chronic heart failure were divided into 3 groups CHF according to NYHA class II similar to IV, and twenty normal volunteers were enrolled. Plasma levels of apelin and PDCD5 antibody were detected by enzyme-linked immunosorbent assay. Results: (1) The plasma levels of apelin in patients with heart failure(NYHA class II similar to IV) were. significantly lower than that in control group, and it was lower in NYHA class III-IV groups than that in NYHA class. group (P <0.05); (2) The plasma levels of PDCD5 were increased in CHF patients(P <0.05). Conclusion: Detecting the plasma levels of apelin and PDCD5 antibody might be usful to evaluate the heart functon.

• 出版日期2013
• 单位郑州大学