A selective quinoline-derived fluorescent chemodosimeter to detect cyanide in aqueous medium

作者：Razi Syed S; Ali Rashid; Srivastava Priyanka; Misra Arvind^*

来源：Tetrahedron Letters, 2014, 55(5): 1052-1056.

DOI：10.1016/j.tetlet.2013.12.080

• Fluorescence
• Chemodosimeter
• CN-
• DFT

A simple quinoline derived probe 3 has been described. Probe 3 having aldehyde function upon interaction with cyanide undergo nucleophilic addition reaction to form cyanohydrin derivative 4 in which fluorescence intensity enhances significantly, %26apos;turn-on%26apos; by photoinduced electron transfer (PET) OFF-ON mechanism. The color of probe solution switched-on to fluorescent blue which is visible to the naked-eye. Job%26apos;s plot analysis revealed a 1:1 stoichiometry for an interaction between 3 and cyanide along with detection limit 0.058 mu M (1.5 ppb). The mode of interaction to detect cyanide in aqueous medium through a reaction based chemodosimeter approach has been confirmed by NMR, mass, FTIR, and DFT data analysis.

• 出版日期2014-1-29