Hepatoprotective potential of petroleum ether leaf extract of Crossandra infundibuliformis on CCl4 induced liver toxicity in albino mice

作者：Madhumitha G; Saral A Mary^*; Senthilkumar B; Sivaraj A

来源：Asian Pacific Journal of Tropical Medicine, 2010, 3(10): 788-790.

DOI：10.1016/S1995-7645(10)60188-5

• Crossandra infundibuliformis
• Hepatic damage

Objective: To analyze the hepatoprotective effect of the Crossandra infundibuliformis. Methods: Hepatotoxicity was induced by carbon tetrachloride. Petroleum ether extract of dried leaves was administrated to mice for 7 days. The hepatoprotective effect of petroleum ether extract was evaluated by the assay of liver function biochemical parameters. Results: The result clearly indicates that petroleum ether extract showed significant hepatoprotection when compared with standard Silumarin. Conclusions: The petroleum ether extract of the leaves of Crossandra infundibuliformis possess significant acute hepatoprotective activity. Thus further investigation on this species would bring a promising drug for liver disorders.

• 出版日期2010-10