Applicability of the Rivermead Behavioural Memory Test - Third Edition (RBMT-3) in Korsakoff%26apos;s syndrome and chronic alcoholics

作者：Wester Arie J; van Herten Judith C; Egger Jos I M; Kessels Roy P C^*

来源：Neuropsychiatric Disease and Treatment, 2013, 9: 875-881.

DOI：10.2147/NDT.S44973

• ecological validity
• neuropsychological assessment
• Korsakoff%26apos
• s syndrome
• alcohol-induced persisting amnestic disorder
• episodic memory
• treatment outcome

Purpose: To examine the applicability of the newly developed Rivermead Behavioural Memory Test - Third Edition (RBMT-3) as an ecologically-valid memory test in patients with alcohol-related cognitive disorders. %26lt;br%26gt;Patients and methods: An authorized Dutch translation of the RBMT-3 was developed, equivalent to the UK version, and administered to a total of 151 participants - 49 patients with amnesia due to alcoholic Korsakoff%26apos;s syndrome, 49 patients with cognitive impairment and a history of chronic alcoholism, not fulfilling the Korsakoff criteria, and 53 healthy controls. Between-group comparisons were made at subtest level, and the test%26apos;s diagnostic accuracy was determined. %26lt;br%26gt;Results: Korsakoff patients performed worse than controls on all RBMT-3 subtests (all P-values %26lt; 0.0005). The alcoholism group performed worse than controls on most (all P-values %26lt; 0.02), but not all RBMT-3 subtests. Largest effects were found between the Korsakoff patients and the controls after delayed testing. The RBMT-3 had good sensitivity and adequate specificity. %26lt;br%26gt;Conclusion: The RBMT-3 is a valid test battery to demonstrate everyday memory deficits in Korsakoff patients and non-Korsakoff patients with alcohol abuse disorder. Korsakoff patients showed an impaired performance on subtests relying on orientation, contextual memory and delayed testing. Our findings provide valuable information for treatment planning and adjustment in patients with alcohol-related cognitive impairments.

• 出版日期2013