Decoding Tat: the biology of HIV Tat posttranslational modifications

作者：Hetzer C; Dormeyer W; Schnolzer M; Ott M^*

来源：Microbes and Infection, 2005, 7(13): 1364-1369.

DOI：10.1016/j.micinf.2005.06.003

• HIV
• Tat
• posttranslational modification

The Tat protein is a viral transactivator that activates HIV transcription through complex interactions with RNA and host cell factors. Tat undergoes multiple posttranslational modifications that regulate the dynamics and complexity of these interactions. The biology of these modifications and their role in Tat function are reviewed.

• 出版日期2005-10