Allergic and Nonallergic Asthma in Children: Are They Distinct Phenotypes?

作者：Mahdaviani Seyed Alireza; Mohajerani Seyed Amir^*; Fakhri Mohammad; Ebrahimi Mazaher; Bashardoost Bahram; Razavi Seyed Jafar; Toolabi Masoumeh; Tajik Ali; Khalilzadeh Soheila; Masjedi Mohamad Reza

来源：Iranian Journal of Allergy, Asthma and Immunology, 2014, 13(5): 370-374.

• Allergic
• Asthma
• Children
• Non allergic
• Phenotype

The aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. %26lt;br%26gt;In a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. Demographic, clinical, and familial history were compared between two groups. %26lt;br%26gt;There was no significant differences between variables like sex, age of onset (p= 0.75), severity (p= 0.70), and family history among the two groups (p= 0.42). Patients with allergic asthma were significantly older than those with non- allergic asthma (11.28 +/- 3.19 and 9.75 +/- 2.35 years, respectively, p= 0.02). %26lt;br%26gt;The controversy lingers over the presence of a completely distinct phenotype of nonatopic asthma in children. Our study suggested that phenotypes of allergic and non- allergic asthma in children were not entirely distinct.

• 出版日期2014-10