Albumin adsorption influence on the stability of the mesoporous zirconia suspension

作者:Szewczuk Karpisz Katarzyna*; Wisniewska Malgorzata; Mysliwiec Dawid
来源:Journal of Industrial and Engineering Chemistry, 2015, 32: 113-119.
DOI:10.1016/j.jiec.2015.08.005

摘要

In this paper, the stability mechanism of the mesoporous zirconia suspension in the albumin presence was described. The albumin adsorption on the zirconia surface depends on pH and ionic strength. The highest adsorption was observed at the albumin IV value (for HSA 3.1 mg/m(2)). The protein adsorption affects the suspension stability. It causes mainly its increase related to electrosteric stabilization phenomenon (pH 3, 6 and 9). At pH 4.6 there is the system destabilization due to the adsorption of the macromolecules with zero net charge. Under these conditions the greatest stability change was also observed (TSI from 8.38 to 23.97).

  • 出版日期2015-12-25