科研之友
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摘要
OBJECTIVE. The objective of our study was to investigate the association between high fovea capitis (fovea alta) and hip dysplasia in young adults.
MATERIALS AND METHODS. In a retrospective study, blinded observers reviewed 82 pelvic radiographic and hip MRI studies of three groups of patients: those with developmental dysplasia of the hip (DDH) (center-edge angle, <= 20 degrees), those with borderline DDH (center-edge angle, 21 degrees - 25 degrees), and control patients (center-edge angle, > 25 degrees). The center-edge angle and coxa valga (femoral neck-shaft angle, > 135) were assessed on pelvic radiographs, and fovea alta was assessed on MR images (delta angle, <= 10 degrees). The Mann-Whitney and Fisher exact tests were used to correlate fovea alta with DDH and with coxa valga, respectively. Interobserver agreement for center-edge and delta angles and the diagnostic performance of fovea alta as a marker of DDH were calculated.
RESULTS. Thirty-one patients with DDH, 23 with borderline DDH, and 28 without DDH were included. Excellent interobserver agreement was found for center-edge angle (concordance correlation coefficient, 0.94) and for delta angle (concordance correlation coefficient, 0.91). Fovea alta had a significant association with DDH (p < 0.001) but no association with coxa valga (p > 0.57). A significant difference (p < 0.001) was found between patients with DDH (3.4 degrees) and those without DDH (21.7 degrees) with respect to mean delta angle measurements. Fovea alta had 69.4% sensitivity, 82.1% specificity, 67.2% positive predictive value, 81.0% negative predictive value, and 75.6% overall accuracy as an indicator of DDH.
CONCLUSION. Fovea alta shows promise as a strong MRI marker of DDH.
- 出版日期2012-10
