Bi(OTf)(3)-catalyzed solvent-free synthesis of pyrano[3,2-c]coumarins through a tandem addition/annulation reaction between chalcones and 4-hydroxycoumarins

作者：Gohain Mukut; van Tonder Johannes H; Bezuidenhoudt Barend C B^*

来源：Tetrahedron Letters, 2013, 54(29): 3773-3776.

DOI：10.1016/j.tetlet.2013.05.008

• Bismuth trifluoromethanesulfonate
• Addition
• 4-Hydroxycoumarin
• Chalcone
• Annulation
• Pyrano[3,2-c]coumarin

A Bi(OTf)(3)-catalyzed tandem addition/annulation reaction is described in order to synthesize pyrano [3,2-c]coumarins under solvent-free conditions. Substituted/unsubstituted chalcones were conveniently condensed with various 4-hydroxycoumarins by means of this environmentally benign method which produces water as the only side product.

• 出版日期2013-7-17