Digital Heart-Rate Variability Parameter Monitoring and Assessment ASIC

作者：Massagram Wansuree^*; Hafner Noah; Chen Mingqi; Macchiarulo Luca; Lubecke Victor M; Boric Lubecke Olga

来源：IEEE Transactions on Biomedical Circuits and Systems, 2010, 4(1): 19-26.

DOI：10.1109/TBCAS.2009.2035555

• Biomedical measurements
• biomedical monitoring
• electrocardiography
• heart-rate variability (HRV)
• beat-to-beat (RR) interval

This paper describes experimental results for an application-specific integrated circuit (ASIC), designed for digital heart rate variability (HRV) parameter monitoring and assessment. This ASIC chip measures beat-to-beat (RR) intervals and stores HRV parameters into its internal memory in real time. A wide range of short-term and long-term ECG signals obtained from Physionet was used for testing. The system detects R peaks with millisecond accuracy, and stores up to 2 min of continuous RR interval data and up to 4 min of RR interval histogram. The prototype chip was fabricated in a 0.5-mu m complementary metal-oxide semiconductor technology on a 3 x 3 mm(2) die area, with a measured dynamic power consumption of 10 mu W and measured leakage current of 2.62 nA. The HRV monitoring system including this HRV ASIC, an analog-to-digital converter, and a low complexity microcontroller was estimated to consume 32.5 mu V, which is seven times lower power than a stand-alone microcontroller performing the same functions. Compact size, low cost, and low power consumption make this chip suitable for a miniaturized portable HRV monitoring system.

• 出版日期2010-2