Procurement strategies for combined multiorgan and composite tissues for transplantation

作者：Datta Neha; Yersiz Hasan; Kaldas Fady; Azari Kodi^*

来源：Current Opinion in Organ Transplantation, 2015, 20(2): 121-126.

DOI：10.1097/MOT.0000000000000172

• multiorgan
• procurement
• protocol
• transplantation
• vascularized composite allograft

Purpose of review
The purpose of this article is to identify the unique aspects of combined multiorgan and vascularized composite allograft (VCA) procurement from deceased donors and outline the steps essential for success.
Recent findings
Transplantation of nonsolid organ composite tissues is becoming a viable option for reconstruction of massive tissue defects. With the United Network for Organ Sharing designation of VCAs as organs, placing them under the domain of the Organ Procurement and Transplantation Network, a systematic method for combined solid organ and VCA procurement is required. Several centers have reported experience with successful procurement strategies including sequential and simultaneous retrievals. The published literature describing donor screening, sequence of procurement with relation to solid organs and allocation is reviewed.
Summary
With the 2013 classification of VCAs as organs, the Organ Procurement and Transplantation Network and United Network for Organ Sharing are better suited to aligning procurement and allocation policies. As VCA transplantation becomes more commonplace, protocol guidelines will ensure smooth integration with existing procurement infrastructure.

• 出版日期2015-4
• 单位UCLA