A quantitative evaluation method using processed optical images and analysis of age-dependent changes on nasolabial lines

作者：Jang Sue Im; Kim Eun Joo; Park Hyeokgon; Kim Hyun Jung; Suk Jang Mi; Kim Beom Joon; Lee John Hwan; Lee Hae Kwang^*

来源：Skin Research and Technology, 2015, 21(2): 201-206.

DOI：10.1111/srt.12177

• nasolabial lines
• aging
• elasticity
• PRIMOS
• optical images
• visual score
• pixel number of NL area
• NL angle

Background/PurposeNasolabial lines (NL) and wrinkles of the face are major features of aging. Wrinkles have been studied widely by morphological methods using 3-dimensional (3D) photographic analysis instrument, but NL were evaluated by visual scoring usually. To evaluate NL quantitatively, another method is needed. This study is purposed to find out quantitative method for evaluation of NL.
MethodOne hundred Korean female subjects aged 20 to 60 were recruited in this study. Facial image was taken using light source adjusted VISIA-CR (R) and 3-dimensional wrinkle depth on the NL area was evaluated by Phase shift rapid in vivo measuring of human skin (PRIMOS (R)). The pixel number of NL area and the angle were obtained using processed images. The severity of NL was assessed by visual score. Skin elasticity was measured by Cutometer((R))MPA580. Statistical significance was determined at P<0.05.
ResultThe optical images obtained by light source adjusted VISIA-CR (R) were easy to distinguish NL and significantly increased age-dependently. And three parameters of elasticity (R2, R5, and R7) on NL area were gradually decreased with age. The Pearson correlation coefficient was -0.756 (P<0.01) between R7 parameter and ages. Also the pixel number of NL area, angle, wrinkle depth on the NL area (Ra), and visual score were decreased elasticity-dependently. The pixel number of NL area was highly related to Ra (r=0.567, P<0.01) and visual score (r=0.647, P<0.01).
ConclusionThis study has shown that NL severity is related to decrease of dermal elasticity and age using quantitative new method by processing optical images.

• 出版日期2015-5