科研之友
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摘要
. Backgrounds: It has not been established whether sex differences in pain perception are influenced by prenatal sex hormones. Digit ratio as an indicator of prenatal hormone exposure can be used as a simple measure of the influence of prenatal hormones on pain sensitivity or perception in adulthood. Objective: The aim of this study was to determine a correlation between the 2D:4D ratio and pain perception in the postoperative period after rhinoplasty. Method: A prospective cohort study of 100 patients (50 women of the mean age of 30.74 +/- 8.09 years and 50 men of the mean age of 30.98 +/- 10.86 years) who underwent posttraumatic rhinoplasty due to the nose trauma in Plastic, Reconstructive and Aesthetic Surgery Clinic. The following measurements were taken the day before a surgery: body height, waist and hip circumference, II and IV digits' lengths and body weight. All subjects filled in a questionnaire including 0-10-point VAS scales to assess postoperative pain 1 h after an operation (AO), 6 h AO, 12 h AO, 24 h AO and 48 h AO. Results: Women with low 2D:4D reported significantly more pain 1 h after an operation than women with high 2D:4D. Similar correlation was observed for low 2D:4D in women 48 h AO. In men, low 2D:4D was associated with lower postoperative pain 12 h AO (p = 0.029). Conclusion: In conclusion, we showed that low 2D:4D in women was associated with high postoperative pain, and low right 2D:4D in men was associated with low postoperative pain. This may suggest that intrauterine estrogen exposure makes women more resistant to pain.
- 出版日期2017-7
