A Fluorinated Cobalt(III) Porphyrin Complex for Hydroalkoxylation of Alkynes

作者：Ushimaru Richiro; Nishimura Takuho; Iwatsuki Toshiki; Naka Hiroshi^*

来源：Chemical & Pharmaceutical Bulletin, 2017, 65(11): 1000-1003.

DOI：10.1248/cpb.c17-00568

• hydroalkoxylation
• acetal
• alkyne
• alcohol
• cobalt
• porphyrin

A fluorinated cobalt(III) porphyrin complex [Co(TPFPP)-NTf2 center dot 2C(2)H(5)OH, where TPFPP=5,10,15,20-tetrakis(penta-fluorophenyl)porphyrin, Tf=CF3SO2] promotes hydroalkoxylation of alkynes to give acetals in good to excellent yields. The acetals can be directly functionalized with nucleophiles in a one-pot procedure.

• 出版日期2017-11