科研之友
微信
新浪微博
Facebook
分享链接
摘要
A catalytic asymmetric carbonyl-ene reaction of beta, gamma-unsaturated alpha-ketoesters with 5-methyleneoxazolines was accomplished. The process was based on the utilization of a chiral N, N '-dioxide/Mg-II catalyst, providing the desired products with excellent outcomes (up to 99% yield, >99% ee) under mild reaction conditions. Based on the experimental investigations and previous reports, a possible transition state was proposed.
- 出版日期2015
- 单位四川大学
