A high yielding, one-pot synthesis of substituted ureas from the corresponding amines using Mitsunobu's reagent

作者：Chaturvedi Devdutt; Mishra Nisha; Mishra Virendra

来源：Monatshefte fur Chemie, 2008, 139(3): 267-270.

DOI：10.1007/s00706-007-0776-1

• Mitsunobu's reagent
• carbon dioxide
• amines
• substituted ureas

A Mitsunobu-based protocol has been developed for the synthesis of symmetrically and unsymmetrically substituted ureas from a variety of primary and secondary amines using gaseous carbon dioxide, in good to excellent yields. This protocol is mild and efficient compared to other reported methods.

• 出版日期2008-3