New chiral polyfunctional cyclobutane derivatives from (-)-verbenone: possible surfactant behaviour

作者：Ospina Jimena; Sorrenti Alessandro; Illa Ona; Pons Ramon^*; Ortuno Rosa M

来源：Tetrahedron: Asymmetry , 2013, 24(12): 713-718.

DOI：10.1016/j.tetasy.2013.05.007

New enantiopure cyclobutane derivatives have been synthesized from a chiral precursor derived from (-)-verbenone. The cyclobutane moiety acts as a chiral platform to afford a gamma-amino acid function in a branched side-chain containing an additional stereogenic centre as well as additional C-6 or C-15-alkyl chains linked to the ring by means of an amine or an amide function. One of these compounds, obtained as a 1:2 mixture with its TFA salt has been investigated, suggesting behaviour as a good surfactant and its critical micellar concentration has been determined.

• 出版日期2013-6-30