Novel Synthetic Route to Fluoxetine

作者：Schulze Matthias^*

来源：Synthetic Communications, 2010, 40(22): 3415-3422.

DOI：10.1080/00397910903422518

• Curtius rearrangement
• fluoxetine
• isocyanate

Racemic fluoxetine was synthesized from 3-benzoylpropionic acid in five steps in 54% overall yield.

• 出版日期2010